Benzodiazepine:  Hypnotic Safety Profile Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. Experimental reproductive effects. Mutation data reported. An anticonvulsant and hypnotic agent. When heated to decomposition it emits toxic fumes of NOx. See also DIAZEPAM. Drug interactions Potentially hazardous interactions with other drugs Antibacterials: metabolism possibly increased by rifampicin. Antipsychotics: increased sedative effects; risk of serious adverse effects in combination with clozapine. Antivirals: concentration possibly increased by ritonavir. Disulfiram: metabolism of nitrazepam inhibited, increased sedative effects. Sodium oxybate: enhanced effects of sodium oxybate - avoid   Metabolism  Metabolised in the liver, mainly by nitroreduction followed by acetylation; none of the metabolites possess significant activity. Excreted in the urine mainly as metabolites.Email : saleroom@yeah.net whatsapp: +8618034511316 wickr/ telegram:  daisey521